[DOWNLOAD] "Drug Design (STAT5 Modulators), Development (Glyceollin I) and Improvement (Esmolol Plus)" by Michael D. Reese # eBook PDF Kindle ePub Free

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eBook details

• Title: Drug Design (STAT5 Modulators), Development (Glyceollin I) and Improvement (Esmolol Plus)
• Author : Michael D. Reese
• Release Date : January 18, 2013
• Genre: Medical,Books,Professional & Technical,
• Pages : * pages
• Size : 6116 KB

Description

This thesis encompasses several different research activities that can contribute to advances within the pharmaceutical arena. The first part of my thesis describes synthetic work directed toward improving the clinical profile of a marketed drug called ‘esmolol’ by developing only its active enantiomer. The second part of the thesis describes my contributions toward the overall scale-up synthesis of a promising anticancer agent called ‘glyceollin I,’ which was undertaken in a team effort. The final part of the thesis describes my efforts to assemble an initial library of compounds that can be used to probe the STAT5 pathway for the potential inhibition of prostate cancer.

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